| Preconception | First Trimester | ||||
---|---|---|---|---|---|---|
VOC (High = ≥ 75th percentile) | Enclave | n (N = 9069) | Odds Ratio (95% CI) | n (N = 9069) | Odds Ratio (95% CI) | |
Benzene | Low | Yes | 242 | Ref. | 245 | Ref. |
No | 4115 | 2.85 (1.57, 5.17)a | 4179 | 2.38 (1.36, 4.16)a | ||
High | Yes | 1649 | 2.07 (1.09, 3.94)a | 1646 | 1.65 (0.90, 3.03) | |
No | 3063 | 3.45 (1.77, 6.72)a | 2999 | 2.70 (1.45, 5.03)a | ||
Ethylbenzene | Low | Yes | 245 | Ref. | 245 | Ref. |
No | 3916 | 2.43 (1.37, 4.32)a | 3943 | 2.30 (1.29, 4.09)a | ||
High | Yes | 1646 | 1.70 (0.90, 3.22) | 1646 | 1.56 (0.82, 2.95) | |
No | 3262 | 2.76 (1.32, 5.75)a | 3235 | 2.29 (1.10, 4.77)a | ||
MTB Ether | Low | Yes | 738 | Ref. | 596 | Ref. |
No | 4578 | 1.38 (1.02, 1.87)a | 4436 | 1.40 (1.01, 1.95) | ||
High | Yes | 1153 | 0.87 (0.58, 1.31) | 1295 | 0.90 (0.60, 1.36) | |
No | 2600 | 1.84 (1.34, 2.52)a | 2742 | 1.88 (1.33, 2.66)a | ||
N-hexane | Low | Yes | 535 | Ref. | 410 | Ref. |
No | 3834 | 1.56 (1.11, 2.20)a | 3984 | 1.72 (1.16, 2.55)a | ||
High | Yes | 1356 | 1.03 (0.68, 1.57) | 1481 | 1.16 (0.74, 1.83) | |
No | 3344 | 2.09 (1.39, 3.15)a | 3194 | 2.25 (1.43, 3.53)a | ||
EMK | Low | Yes | 739 | Ref. | 627 | Ref. |
No | 4827 | 1.62 (1.19, 2.20)a | 4615 | 1.43 (1.04, 1.96)a | ||
High | Yes | 1152 | 1.09 (0.72, 1.63) | 1264 | 0.85 (0.57, 1.28) | |
No | 2351 | 1.84 (1.32, 2.58)a | 2563 | 1.67 (1.18, 2.36)a | ||
m-xylene | Low | Yes | 245 | Ref. | 245 | Ref. |
No | 3909 | 2.33 (1.31, 4.15)a | 3926 | 2.30 (1.29, 4.08)a | ||
High | Yes | 1646 | 1.59 (0.84, 3.01) | 1646 | 1.55 (0.82, 2.94) | |
No | 3269 | 2.40 (1.15, 5.00)a | 3252 | 2.27 (1.08, 4.76)a | ||
o-xylene | Low | Yes | 304 | Ref. | 246 | Ref. |
No | 3897 | 2.37 (1.42, 3.98)a | 3936 | 2.35 (1.32, 4.17)a | ||
High | Yes | 1587 | 1.66 (0.94, 2.94) | 1645 | 1.60 (0.85, 3.04) | |
No | 3281 | 2.52 (1.30, 4.87)a | 3242 | 2.42 (1.15, 5.09)a | ||
p-xylene | Low | Yes | 438 | Ref. | 338 | Ref. |
No | 3868 | 1.87 (1.25, 2.78)a | 3900 | 1.93 (1.23, 3.03)a | ||
High | Yes | 1453 | 1.27 (0.80, 2.03) | 1553 | 1.29 (0.77, 2.16) | |
No | 3310 | 2.02 (1.20, 3.40)a | 3278 | 1.93 (1.06, 3.53)a | ||
Propene | Low | Yes | 827 | Ref. | 945 | Ref. |
No | 4728 | 1.44 (1.07, 1.93)a | 4471 | 1.45 (1.09, 1.93)a | ||
High | Yes | 1064 | 0.93 (0.64, 1.36) | 946 | 0.94 (0.66, 1.34) | |
No | 2450 | 1.99 (1.46, 2.72)a | 2707 | 1.96 (1.44, 2.67)a | ||
Sesquiterpene | Low | Yes | 818 | Ref. | 741 | Ref. |
No | 3753 | 1.55 (1.15, 2.10)a | 3841 | 1.38 (1.02, 1.87)a | ||
High | Yes | 1073 | 1.13 (0.77, 1.65) | 1150 | 0.87 (0.59, 1.28) | |
No | 3425 | 2.23 (1.59, 3.14)a | 3337 | 1.91 (1.36, 2.69)a | ||
Toluene | Low | Yes | 334 | Ref. | 245 | Ref. |
No | 3891 | 2.39 (1.45, 3.95)a | 3934 | 2.31 (1.30, 4.11)a | ||
High | Yes | 1557 | 1.68 (0.96, 2.91) | 1646 | 1.57 (0.83, 2.97) | |
No | 3287 | 2.38 (1.25, 4.52)a | 3244 | 2.31 (1.09, 4.89)a | ||
Styrene | Low | Yes | 736 | Ref. | 619 | Ref. |
No | 6268 | 1.41 (1.04, 1.93)a | 6266 | 1.47 (1.05, 2.06)a | ||
High | Yes | 1155 | 0.84 (0.56, 1.26) | 1272 | 0.89 (0.59, 1.34) | |
No | 910 | 1.59 (1.13, 2.24)a | 912 | 1.56 (1.08, 2.25)a | ||
1,3 butadiene | Low | Yes | 732 | Ref. | 595 | Ref. |
No | 6197 | 1.39 (1.02, 1.88)a | 6354 | 1.48 (1.06, 2.06)a | ||
High | Yes | 1159 | 0.83 (0.55, 1.25) | 1296 | 0.86 (0.57, 1.29) | |
No | 981 | 1.67 (1.19, 2.33)a | 824 | 1.46 (1.01, 2.13)a | ||
Cyclohexane | Low | Yes | 1022 | Ref. | 1016 | Ref. |
No | 3747 | 1.86 (1.37, 2.53)a | 3794 | 1.70 (1.26, 2.28)a | ||
High | Yes | 869 | 1.31 (0.92, 1.87) | 875 | 1.08 (0.76, 1.54) | |
No | 3431 | 1.73 (1.15, 2.59)a | 3384 | 1.46 (0.98, 2.18) |