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Table 2 Regression analyses of WBCs adjusted for plasma fluoride, age, gender, ethnicity, and BMI*

From: Fluoride exposure and blood cell markers of inflammation in children and adolescents in the United States: NHANES, 2013–2016

 

Plasma F

Age

Female

Ethnicity (Black)

Ethnicity (Hispanic)

Ethnicity (Asian)

Ethnicity (Other/Mulit)

BMI

Constant

N subpop weighted (raw)

Dependent Variable

WBC

0.482 (0.107, 0.858)

-0.089 (-0.124, -0.053)

0.397 (0.213, 0.581)

-0.879 (-1.023, -0.074)

0.257 (0.063, 0.450)

0.179 (-0.230, 0.588)

0.082 (-0.298, 0.462)

0.094 (0.071, 0.118)

5.838 (5.392, 6.283)

38,715,039 (3,453)

p = 0.014

p < 0.000

p < 0.000

p < 0.000

p < 0.011

p = 0.378

p = 0.462

p < 0.000

p < 0.000

Lymph

0.076 (-0.047, 0.198)

-0.072 (-0.081, -0.063)

0.139 (0.075, 0.205)

-0.160 (-0.237, -0.084)

0.045 (-0.05, 0.133)

0.117 (-0.013, 0.246)

-0.236 (-0.164, 0.117)

0.017 (0.022, 0.021)

2.952 (2.770, 3.133)

38,659,063 (3,447)

p = 0.217

p < 0.000

p < 0.000

p < 0.000

p = 0.365

p = 0.075

p = 0.735

p < 0.001

p < 0.000

Neutro

0.364 (0.042, 0.685)

-0.012 (-0.030, 0.028)

0.306 (0.173, 0.440)

-0.684 (-0.780, -0.588)

0.202 (0.084, 0.320)

0.079 (-0.209, 0.388)

0.097 (-0.194, 0.389)

0.070 (0.051, 0.089)

1.994 (1.672, 2.317)

38,659,063 (3,447)

p = 0.028

p < 0.936

p < 0.000

p < 0.000

p = 0.002

p = 0.581

p = 0.501

p < 0.000

p < 0.000

Mono

0.041 (0.011, 0.072)

-0.004 (-0.007, -0.002)

-0.006 (-0.020, 0.008)

-0.52 (-0.072, -0.31)

-0.011 (-0.29, 0.007)

-0.39 (-0.72, -0.031)

-0.005 (-0.037, 0.027)

0.006 (0.005, 0.008)

0.482 (0.441, 0.524)

38,659,063 (3,447)

p = 0.009

p < 0.001

p = 0.366

p < 0.000

p = 0.214

p = 0.027

p = 0.748

p < 0.000

p < 0.000

Eosino

-0.0002 (-0.021, 0.021)

-0.010 (-0.013, -0.007)

-0.037 (-0.054, -0.020)

0.023 (-0.006, .053)

0.026 (-0.005, 0.058)

0.024 (-0.019, 0.066)

0.016 (-0.023, 0.056)

0.001 (-0.001, 0 .002)

0.363 (0.312, 0.414)

38,659,063 (3,447)

p = 0.981

p < 0.000

p < 0.000

p = 0.113

p = 0.100

P = 0.263

p = 0.860

p < 0.001

p < 0.001

Baso

0.003 (-0.007, 0.012)

-0.001 (-0.002, 0.007)

-0.002 (-0.006, 0.003)

-0.001 (-0.008, 0.005)

0.002 (-0.005, 0.009)

0.003 (-0.003, 0.01)

-0.001 (-0.011, 0.008)

.0007 (0.000, 0.001

0.039 (0.031, 0.047)

38,659,063 (3,447)

p = 0.558

p < 0.000

p = 0.514

p = 0.070

p = 0.556

p = 0.284

p = 0.753

p = 0.003

p < 0.001

Water F

0.296 (0.167, 0.426)

-0.003 (0.010, 0.005)

-0.003 (-0.031, 0.025)

0.106 (0.026, 0.187)

0.091 (0.001, 0.181)

0.03 (-0.034, 0.093)

0.003 (-0.075, 0.080)

.002 (-0.003, 0.008)

0.370 (0.218, 0.523)

37,854,276 (3,396)

p < 0.000

p = 0.443

p = 0.816

p = 0.011

p = 0.048

p = 0.347

p = 0.07

p = 0.405

p < 0.000

  1. *Confidence levels, 95% upper and lower confidence intervals (brackets) and the p value are listed for each set of independent and dependent variables tested in the regression model using weighted values. Significant values (p < 0.05) are highlighted
  2. *Ethnicity = white is the reference group; the omnibus test of ethnicity is statistically significant for WBC, Lymph, Neutro and Mono
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Environmental Health

ISSN: 1476-069X