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Table 2 Association between transportation noise source and diabetes mortality. Full cohort including 4,136,220 adults over 30 years, followed from 2001 to 2015. Multipollutant models, adjusting for the other two noise sources plus NO2. HR and 95% confidence intervals (CI) per 10 dB increase in Lden noise source

From: Long-term exposure to transportation noise and diabetes mellitus mortality: a national cohort study and updated meta-analysis

Outcome definition

Main: nonT1-DM

Secondary 1: DM

Secondary 2: T1-DM

ICD-10: E11-E14

IDC-10: E10-E14

ICD-10: E10

N deaths

72,342

73,388

1046

Noise source

Road traffic

Railway

Aircraft

Road traffic

Railway

Aircraft

Road traffic

Railway

Aircraft

Model 0

1.08

(1.07, 1.09)

1.04

(1.03, 1.05)

0.97

(0.96, 0.98)

1.08

(1.07, 1.09)

1.04

(1.03, 1.05)

0.97

(0.96, 0.98)

1.17

(1.09, 1.27)

1.04

(0.99, 1.10)

1.00

(0.92, 1.08)

Model 1

1.06

(1.05, 1.07)

1.03

(1.02, 1.03)

1.02

(1.01, 1.03)

1.06

(1.05, 1.07)

1.03

(1.02, 1.03)

1.02

(1.01, 1.03)

1.14

(1.06, 1.23)

1.04

(0.98, 1.10)

1.00

(0.92, 1.09)

Model 2

1.06

(1.05, 1.07)

1.02

(1.02, 1.03)

1.01

(1.00, 1.02)

1.06

(1.05, 1.07)

1.02

(1.02, 1.03)

1.01

(1.00, 1.02)

1.13

(1.04, 1.22)

1.02

(0.96, 1.08)

0.94

(0.84, 1.04)

Model 3

(main model)

1.06

(1.05, 1.07)

1.02

(1.01, 1.03)

1.01

(0.99, 1.02)

1.06

(1.05, 1.07)

1.02

(1.01, 1.03)

1.01

(0.99, 1.02)

1.09

(1.01, 1.18)

1.02

(0.96, 1.08)

0.92

(0.83, 1.03)

Model 3b

1.06

(1.05, 1.07)

1.02

(1.02, 1.03)

1.01

(0.99, 1.02)

1.06

(1.05, 1.07)

1.02

(1.02, 1.03)

1.00

(0.99, 1.02)

1.12

(1.03, 1.21)

1.02

(0.96, 1.08)

0.92

(0.82, 1.02)

Model 4.1

1.06

(1.05, 1.07)

1.02

(1.01, 1.03)

1.01

(0.99, 1.02)

1.06

(1.05, 1.07)

1.02

(1.01, 1.03)

1.01

(0.99, 1.02)

1.09

(1.00, 1.18)

1.01

(0.95, 1.08)

0.92

(0.83, 1.03)

Model 4.2

1.04

(1.03, 1.05)

1.02

(1.02, 1.03)

1.01

(1.00, 1.02)

1.04

(1.03, 1.06)

1.02

(1.02, 1.03)

1.01

(0.99, 1.02)

1.08

(0.97, 1.19)

1.03

(0.97, 1.09)

0.93

(0.83, 1.03)

  1. Notes:
  2. Model 0 included noise exposure (road traffic, railway and aircraft noise; Lden), strata sex and period (i.e. 2001–2005, 2006–2010, or 2011–2015)
  3. Model 1 included Model 0 + the individual-level covariates civil status, education level, mother tongue, nationality and quartiles of local-SEP
  4. Model 2 included Model 1 + community and regional SEP score and unemployment
  5. Model 3 (main model) included Model 2 + quartiles of NO2 exposure
  6. Model 3b included Model 2 + quartiles PM2.5 exposure
  7. Model 4.1 included Model 3 + quartiles of intermittency ratio (IR) at night
  8. Model 4.2 included Model 3 + quartiles of number of noise events at night