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Table 4 Total effect of 18 POPs and important exposures identified from WQS with each LOD accommodation approach, with NHANES 2001–2002

From: Accommodating detection limits of multiple exposures in environmental mixture analyses: an overview of statistical approaches

 

Total effect \(\boldsymbol\psi\) (SE)

Important exposures (weight)

Complete case

0.014 (0.009)

PCB169 (0.538), 1,2,3,4,6,7,8-hxcdf (0.125), PCB126 (0.113)

LOD/\(\sqrt{2}\)

0.018 (0.005)

2,3,4,7,8-pncdf (0.350), PCB126 (0.186), 1,2,3,4,6,7,8-hxcdf (0.184)

MI

0.015 (0.006)

PCB169 (0.580), 1,2,3,4,6,7,8-hxcdf (0.153), PCB126 (0.080)

Truncated MI

0.018 (0.005)

2,3,4,7,8-pncdf (0.346), PCB126 (0.186), 1,2,3,4,6,7,8-hxcdf (0.183)

F-AFT

0.017 (0.005)

2,3,4,7,8-pncdf (0.328), PCB126 (0.189), 1,2,3,4,6,7,8-hxcdf (0.184), PCB194 (0.062)

  1. Relative importance was reported for exposures with the weight over 1/18
  2. Abbreviations: Imputation by LOD/\(\sqrt{2}\) (LOD/\(\sqrt{2}\)), MI Conventional multiple imputation, Truncated MI Truncated multiple imputation, F-AFT Imputation by estimates using the AFT model
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Environmental Health

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