Table 3 Bivariate analysis. Note that every level value is relative to reference

A. Bivariate association between MetS score outcome and glyphosate level by exposure quartile

Glyphosate

Estimate

95% CI

p value

Quartile 1 (ref)

-0.072

-0.126, -0.018

-

Quartile 2

0.071

-0.005, 0.148

0.069

Quartile 3

0.127

0.051, 0.204

0.001

Quartile 4

0.090

0.014, 0.167

0.021

B. Exposure and outcome by race/ethnicity

Log(Glyphosate) exposure by Race

Race/Ethnicity

Estimate

95% CI

p value

Pr(> F)

White (ref)

0.530

0.504, 0.555

-

F = 8.35

p < 0.0001

Mexican–American

-0.076

-0.123, -0.029

0.002

Other Hispanic

-0.030

-0.086, 0.026

0.291

Black

0.038

-0.005, 0.081

0.083

Asian

-0.110

-0.164, -0.055

0.0001

Multiracial

0.037

-0.039, 0.114

0.33

Standardized MetS score (outcome) by Race

White (ref)

-0.040

-0.084, 0.004

-

F = 19.0

p < 0.0001

Mexican–American

0.089

0.008, 0.170

0.030

Other Hispanic

0.083

-0.013, 0.180

0.090

Black

0.112

0.038, 0.187

0.003

Asian

-0.063

-0.156, 0.031

0.188

Multiracial

0.018

-0.114, 0.149

0.792

C. Exposure and Outcome by Age Category

Log(Glyphosate) exposure by Age Grouping

Age Category

Estimate

95% CI

p value

Pr(> F)

10-19yrs (ref)

0.586

0.553, 0.62

-

F = 22.6

p < 0.0001

20-39yrs

-0.136

-0.182, -0.09

 < 0.0001

40-59yrs

-0.125

-0.170, -0.08

 < 0.0001

 > 60yrs

-0.025

-0.070, 0.02

0.281

Standardized MetS score (outcome) by Age Grouping

10-19yrs (ref)

-0.695

-0.745, -0.645

-

F = 4113

p < 0.0001

20-39yrs

0.385

0.317, 0.454

 < 0.0001

40-59yrs

0.966

0.898, 1.034

 < 0.0001

 > 60yrs

1.308

1.240, 1.376

 < 0.0001

D. Exposure and outcome by sex

Glyphosate exposure by Sex

Sex

Estimate

95% CI

p value

Male (ref)

0.546

0.524, 0.568

-

Female

-0.067

-0.099, -0.036

 < 0.0001

Standardized MetS score (outcome) by Sex

Male (ref)

0.070

0.031, 0.108

-

Female

-0.139

-0.193, -0.085

 < 0.0001