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Table 4 Hazard ratios (HR) and 95% confidence intervals (CI) for the Marines/Navy personnel subgroup analysis of base location at Camp Lejeune (CL) vs. Camp Pendleton (CP); underlying cause of death

From: Evaluation of mortality among Marines, Navy personnel, and civilian workers exposed to contaminated drinking water at USMC base Camp Lejeune: a cohort study

Outcome

Total

Camp Lejeune #

Unadjusted

HR (95% CI)

Adjusted

HR (95% CI)

Camp Pendleton #

All causes

40,384

19,250

0.98(0.96, 1.00)

0.99(0.97, 1.01)

21,134

All cancer malignancies

7,449

3,689

1.06(1.01, 1.11)

1.06(1.02, 1.11)

3,760

Oral cancers

230

106

0.92(0.71, 1.19)

0.95(0.73, 1.24)

124

Pharyngeal cancer

121

56

0.93(0.65, 1.33)

0.94(0.66, 1.35)

65

Esophageal cancer

325

171

1.20(0.97, 1.49)

1.24 (1.00, 1.54)

154

Stomach cancers

189

89

0.96(0.72, 1.28)

0.92(0.69, 1.23)

100

Colorectal cancers

707

349

1.05(0.91, 1.22)

1.03(0.88, 1.19)

358

Colon cancer

530

266

1.09(0.92, 1.29)

1.05(0.89, 1.25)

264

Rectal cancer

177

83

0.95(0.71, 1.27)

0.94(0.70, 1.27)

94

Liver cancer

557

268

1.00(0.85, 1.19)

1.06(0.89, 1.25)

289

Pancreatic cancer

515

265

1.14(0.96, 1.36)

1.14(0.96, 1.36)

250

Laryngeal cancer

75

36

1.00(0.64, 1.57)

1.01(0.64, 1.58)

39

Lung cancer

1,897

982

1.16(1.06, 1.27)

1.18(1.07, 1.29)

915

Bone cancers

40

16

0.71(0.38, 1.34)

0.74(0.39, 1.39)

24

Soft tissue cancers

103

53

1.14(0.77, 1.67)

1.12(0.76, 1.65)

50

Melanoma

214

105

1.03(0.79, 1.35)

1.07(0.82, 1.40)

109

Female Breast cancer

66

41

1.27(0.77, 2.08)

1.20 (0.73, 1.98)

25

Male Breast cancer

15

4

0.39(0.13, 1.24)

0.36 (0.12, 1.14)

11

Cervical cancer

14

9

1.19(0.39, 3.65)

1.25 (0.40, 3.85)

5

Uterine cancer

12

5

0.62(0.20, 1.97)

0.62 (0.20, 1.98)

7

Ovarian cancer

14

8

1.12(0.39, 3.24)

1.23 (0.42, 3.59)

6

Prostate cancer

203

95

0.97(0.74, 1.28)

0.93 (0.71, 1.23)

108

Testicular cancer

30

18

1.62(0.78, 3.36)

1.76 (0.85, 3.67)

12

Bladder cancer

127

61

1.00(0.71, 1.42)

1.02(0.72, 1.45)

66

Kidney cancer

265

139

1.19(0.93, 1.51)

1.21(0.95, 1.54)

126

Brain and CNS cancers

395

178

0.88(0.72, 1.07)

0.89(0.73, 1.09)

217

Thyroid cancer

20

8

0.71(0.29, 1.74)

0.71(0.29, 1.74)

12

Hematopoietic cancers

734

354

1.00(0.86, 1.16)

0.99(0.86, 1.14)

380

Hodgkin lymphoma

62

30

1.00(0.61, 1.64)

0.98(0.59, 1.61)

32

Non-Hodgkin lymphoma

273

122

0.87(0.68, 1.10)

0.87(0.68, 1.10)

151

Multiple myeloma

123

62

1.10(0.77, 1.56)

1.07(0.75, 1.53)

61

Leukemias

278

142

1.12(0.89, 1.42)

1.10(0.87, 1.40)

136

ALL

45

20

0.85(0.47, 1.53)

0.85(0.47, 1.53)

25

CLL

15

7

0.94(0.34, 2.59)

0.89(0.32, 2.48)

8

AML

122

62

1.12(0.78, 1.59)

1.11(0.78, 1.59)

60

CML

28

11

0.69(0.32, 1.47)

0.65(0.30, 1.40)

17

MDS

17

11

1.96(0.73, 5.30)

2.26(0.83, 6.17)

6

Lymphoid cancers

63

27

0.82(0.50, 1.35)

0.80(0.49, 1.33)

36

Myeloid cancers

157

79

1.12(0.82, 1.53)

1.10(0.80, 1.50)

78

Diabetes

852

400

0.96(0.84, 1.10)

0.96(0.83, 1.09)

452

Anemias

25

12

1.00(0.46, 2.19)

0.89(0.41, 1.97)

13

Cardiovascular disease

8,966

4,316

1.00(0.96, 1.04)

0.99(0.95, 1.03)

4,650

Heart disease

7,331

3,512

0.99(0.95, 1.04)

0.99(0.94, 1.03)

3,819

Stroke

861

432

1.08(0.95, 1.24)

1.05(0.92, 1.20)

429

Circulatory diseases

773

371

0.99(0.86, 1.14)

0.95(0.82, 1.09)

402

COPD

632

312

1.06(0.91, 1.24)

1.08(0.93, 1.27)

320

Chronic Liver disease

1,389

614

0.85(0.77, 0.95)

0.93(0.83, 1.03)

775

Cirrhosis

1,560

693

0.86(0.78, 0.95)

0.93(0.84, 1.03)

867

Alcoholic Liver disease

901

381

0.79(0.69, 0.90)

0.86(0.76, 0.99)

520

Nonalcoholic Liver disease

488

233

0.98(0.82, 1.17)

1.06(0.89, 1.27)

255

Acute Kidney disease

42

18

0.81(0.44, 1.50)

0.81(0.44, 1.50)

24

Chronic Kidney disease

272

133

1.03(0.82, 1.31)

0.96(0.75, 1.22)

139

Parkinson disease

23

15

2.09(0.89, 4.94)

2.05(0.86, 4.87)

8

ALS

131

64

1.03(0.73, 1.45)

1.04(0.73, 1.46)

67

Multiple sclerosis

56

29

1.18(0.70, 1.99)

1.18(0.70, 2.00)

27

Alcoholism

544

242

0.86(0.72, 1.02)

0.90(0.76, 1.07)

302

Suicide

3,666

1,664

0.88(0.83, 0.94)

0.93(0.87, 0.99)

2,002

  1. CL = 159,128 Males = 151,026 Females = 8,102; CP = 168,406 Males = 162,473 Females = 5,933; Total = 327,534 Males = 313,499 Females = 14,035; COPD: chronic obstructive pulmonary disease; ALS: amyotrophic lateral sclerosis; MDS: myelodysplastic syndrome; CML: chronic myeloid leukemia; AML: acute myeloid leukemia; CLL: chronic lymphocytic leukemia; ALL: acute lymphocytic leukema; CNS: central nervous system
  2. HRs adjusted for sex, race, rank and education level; age was the time variable