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Table 1 Summary of studies investigating the effect of alcohol consumption on thermoregulation, cardiovascular responses, hydration markers, and biomarkers in the heat. Data presented as means with standard deviation, unless otherwise stated. Alcohol dosages have been standardized to grams of alcohol per kilogram of body mass and blood alcohol content has been standardized to grams of alcohol per liter of blood, with original units given in parentheses. BAC blood alcohol content

From: The effect of alcohol consumption on human physiological and perceptual responses to heat stress: a systematic scoping review

Article and origin

Study population

Protocol

Dose, Control, Delivery, and Blood Alcohol Content

Passive heat exposure (air)

Yoda, 2005 [38]

Japan

N = 8 (8 M, 0F)

Age: 26 ± 11 years

Population: healthy alcohol-tolerant men

90 min exposure to 33 °C and 50%RH air

Dose: 0.36 g/kg of ethanol

Delivery: Oral ingestion

Control: Volume-matched distilled water

BAC: Not measured

Livingstone, 1980 [35]

Canada

N = 8 (8 M, 0F)

Age: 25 ± 5 years

Population: Young healthy Caucasians

90 min passive exposure in 30 °C and 40%RH air, pre-ingestion and 120 min post-ingestion

Dose: 50 cc of pure ethanol

Delivery: Oral ingestion

Control: 50 cc of orange juice

BAC: Not measured

Gibiński, 1979 [33]

Poland

N = CON: 12 (12 M, 0F)

ALC: 15 (15 M, 0 F)

Age: 29—41 years (range)

Population: Healthy adults

120 min exposure to 43 °C air

Dose: 0.78 g/kg (150 ml of 45% ethanol)

Delivery: Oral ingestion

Control: Ad libitum water consumption

BAC: Not measured

Passive heat exposure (water)

Allison, 1992 [31]

US

N = 6 (6 M, 0F)

Age: 31 ± 6 years

Population: healthy adults

40 °C water immersion for 21 min

Dose: 0.27 or 0.54 g/kg of 151 proof rum, in 350 ml of caffeine and sugar free cola

Delivery: Oral ingestion

Control: 350 ml of caffeine and sugar free cola

BAC: 0.040 ± 1 0.011 g/dl; 0.077 ± 0.015 g/dl

Mekjavic, 1987 [36]

Canada

N = 6 (6 M, 0F)

Age: Not reported

Population: Young healthy men

40 °C water immersion for 60 min

Dose: 0.79 g/kg (2.5 ml/kg of 40% ethanol) in a 1:2 ratio to orange juice

Delivery: Oral ingestion

Control: 7.5 ml/kg of orange juice

BAC: 0.078 ± 0.01 g/dL (0.078 ± 0.01 g%)

Exercise in hot environments

Jiménez-Pavón, 2015 [34]

Spain

N = 22 (22 M, 0F)

Age: 21 ± 1 years

Population: Physically active men

60 min running at 60% VO2max in 35 °C and 60%RH

Dose: 0.32 g/kg (660 ml of 4.5% beer) post-exercise followed by ad libitum water consumption

Delivery: Oral ingestion

Control: Ad libitum water consumption

BAC: not measured

Desruelle, 1996 [32]

France

N = 8 (6 M, 0F)

Age: Not reported

Population: Healthy adults

60 min of exercise at 45% VO2max in 35 °C and 45% RH

Dose: 1.20 g/kg of ethanol in a 600 ml cocktail

Delivery: Oral ingestion

Control: volume-matched placebo cocktail

BAC: 0.11 g/dL (SD not reported)

Saini, 1995 [37]

France

N = 8 (8 M, 0F)

Age: 23 ± 3 years

Population: Healthy men

60 min cycling at 45%VO2max in 35 °C, 35% RH

Dose: 1.20 g/kg of ethanol (vodka) mixed with 345 ml of orange juice

Delivery: Oral ingestion

Control: 345 ml orange juice with water to match volume

BAC: 0.108 g/dl (SD not reported) (23.5 mmol/l)