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Table 4 Associations between occupational solvent exposure during pregnancy and child behavior at ages 2, 6 and 12 (PELAGIE mother-child cohort, France, N = 459)

From: Occupational exposure to organic solvents during pregnancy and child behavior from early childhood to adolescence

Behavior score

Self-reported exposure

N

2 years

6 years

12 years

 

Direct

effect

Total (direct + indirect effect)

Direct

effect

Total (direct + indirect effect)

Stand.coeff. a (95%CI)

Stand.coeff. a (95%CI)

Stand.coeff. a (95%CI)

Stand.coeff. a (95%CI)

Stand.coeff. a (95%CI)

Internalizing

None

230

ref.

ref.

ref.

ref.

ref.

 

Occasional

88

0.14 (-0.09, 0.36)

0.29 (0.00, 0.59)

0.37 (0.06, 0.68)

0.02 (-0.33, 0.36)

0.27 (-0.08, 0.62)

 

Regular

141

0.16 (-0.06, 0.38)

0.07 (-0.21, 0.35)

0.15 (-0.14, 0.44)

0.03 (-0.26, 0.33)

0.14 (-0.17, 0.46)

Externalizing

None

230

ref.

ref.

ref.

ref.

ref.

 

Occasional

88

0.28 (-0.01, 0.57)

-0.04 (-0.31, 0.24)

0.09 (-0.20, 0.38)

0.16 (-0.11, 0.43)

0.20 (-0.07, 0.48)

 

Regular

141

0.23 (-0.05, 0.51)

-0.11 (-0.36, 0.15)

-0.01 (-0.28, 0.26)

0.20 (-0.04, 0.45)

0.19 (-0.08, 0.45)

  1. 95% CI, 95% Confidence Interval; SEM: structural equation model; SD: standard deviation
  2. aSEM standardized regression coefficients, expressed in number of SD of the latent variable. Models were adjusted for child sex, maternal education level, maternal age, breastfeeding duration, smoking during pregnancy, parity, and mother-child interaction score. Fit indices: Chi Square = 122.885, df = 109, p = 0.17; RMSEA = 0.034; GFI = 0.999; CFI = 0.990; SRMR = 0.030