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Table 5 Associations between occupational solvent exposure during pregnancy and child behavior at ages 2, 6 and 12 for boys (N = 236) and girls (N = 223) (PELAGIE mother-child cohort, France)

From: Occupational exposure to organic solvents during pregnancy and child behavior from early childhood to adolescence

Behavior score

Self-reported exposure

N

2 years

6 years

12 years

 

Direct effect

Total (direct + indirect) effect

Direct effect

Total (direct + indirect) effect

Stand.coeff. a (95%CI)

Stand.coeff. a (95%CI)

Stand.coeff. a (95%CI)

Stand.coeff. a (95%CI)

Stand.coeff. a (95%CI)

    

Boys

   

Internalizing

None

121

ref.

ref.

ref.

ref.

ref.

 

Occasional

37

0.06 (-0.26, 0.38)

0.05 (-0.34, 0.43)

0.11 (-0.27, 0.49)

0.19 (-0.27, 0.65)

0.26 (-0.22, 0.73)

 

Regular

78

0.26 (-0.03, 0.56)

0.04 (-0.34, 0.42)

0.16 (-0.23, 0.54)

-0.05 (-0.43, 0.33)

0.05 (-0.36, 0.46)

Externalizing

None

121

ref.

ref.

ref.

ref.

ref.

 

Occasional

37

0.31 (-0.09, 0.72)

-0.20 (-0.59, 0.19)

-0.05 (-0.45, 0.36)

0.04 (-0.38, 0.46)

-0.01 (-0.43, 0.41)

 

Regular

78

0.28 (-0.09, 0.65)

-0.36 (-0.70, -0.03)

-0.22 (-0.56, 0.12)

0.29 (-0.07, 0.66)

0.08 (-0.31, 0.47)

    

Girls

   

Internalizing

None

109

ref.

ref.

ref.

ref.

ref.

 

Occasional

51

0.21 (-0.09, 0.51)

0.47 (-0.01, 0.94)

0.56 (0.06, 1.06)

-0.11 (-0.63, 0.41)

0.29 (-0.21, 0.80)

 

Regular

63

0.02 (-0.31, 0.36)

-0.07 (-0.52, 0.38)

-0.04 (-0.50, 0.41)

0.35 (-0.12, 0.83)

0.21 (-0.23, 0.65)

Externalizing

None

109

ref.

ref.

ref.

ref.

ref.

 

Occasional

51

0.26 (-0.16, 0.68)

0.13 (-0.32, 0.58)

0.23 (-0.21, 0.68)

0.20 (-0.17, 0.56)

0.45 (0.06, 0.83)

 

Regular

63

0.18 (-0.25, 0.60)

0.35 (-0.05, 0.74)

0.44 (0.00, 0.88)

0.20 (-0.18, 0.58)

0.40 (0.03, 0.76)

  1. 95% CI, 95% Confidence Interval; SEM: structural equation model; SD: standard deviation
  2. aSEM standardized regression coefficients, expressed in number of SD of the latent variable
  3. Factor loadings, covariances between latent variables and between subscales at subsequent time point were constrained to equality between boys and girls
  4. Models were adjusted for maternal education level, maternal age, breastfeeding duration, smoking during pregnancy, parity, and mother-child interaction score. Fit indices: Chi Square = 205.525, df = 222, p = 0.78; RMSEA = 0.035; GFI = 0.999; CFI = 1.0; SRMR = 0.039