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Table 4 Cohort Details

From: Quantifying the association between PM2.5 air pollution and IQ loss in children: a systematic review and meta-analysis

Study

Cohort Size

Location

Cohort Name (if applicable)

Recruitment Strategy

Age at Cognitive Testing

Harris et al. (2015) [7]

1109

Massachusetts, USA

Project Viva Cohort

Pregnant people-child pairs enrolled during 1999-2002 at birthing individual’s initial prenatal visits (median, 9.9 weeks of gestation) at eight locations of Atrius Harvard Vanguard Medical Associates, a multi-subspecialty group practice in urban and suburban eastern Massachusetts.

8 years

Porta et al. (2016) [9]

474

Rome, Italy

Gene and Environment Prospective Study on Infancy in Italy (GASPII)

Newborns enrolled at two large obstetric hospitals in Rome in 2003-2004. The eligible population included infants born to women ages 18 years or older and residents of one of the five local health districts in the city.

7 years

Wang et al. (2017) [10]

1085

California, USA

Risk Factors for Antisocial Behavioral (RFAB) twin study

Families were recruited from Los Angeles and surrounding counties, with the resulting sample representative of a socio-economically-diverse multi-ethnic population residing in the greater Los Angeles areas.

9-11 and 18-20 years

Seifi et al. (2021) [12]

369

Buscher providence, Iran

N/A

Children selected from schools in three low-privileged areas in Bushehr province, southern Iran between 2019-2020.

6-8 years

Ni et al. (2022) [11]

1311

California, New York, Minnesota, Washington, USA

Environmental Influences on Child Health Outcomes (ECHO)a

Conditions Affecting Neurocognitive Development and Learning in Early Childhood (CANDLE)

From 2006-2011 birthing individuals considered eligible if 16-40 years of age, had medically low-risk singleton pregnancies, and planned to deliver in a participating study hospital.

The Infant Development and Environment Study (TIDES) From 2010-2012 recruitment commenced in academic medical centers in four cities: San Francisco, California; Rochester, New York; Minneapolis, Minnesota; and Seattle, Washington. Pregnant individuals in the first trimester were considered eligible if over 18 years of age, were English-speaking, and planned to deliver at a participating study hospital.

Global Alliance to Prevent Prematurity and Stillbirths (GAPS) From 2017-2020 birthing parent-child dyads were recruited from Seattle and Yakima, Washington if they had consented to prenatal questionnaire data and biospecimen collection.

4-6 years

Sun et al. (2023) [8]

512

Shanghai, China

Shanghai-Minhang Birth Cohort

Pregnant people who underwent their first prenatal examination at 12-16 weeks of gestation in the Minhang Maternal and Child Health Hospital in 2012.

6 years

  1. The six studies included for the final review represent a total of 4860 children across three continents (North America, Europe, and Asia). The average age at cognitive testing was 8.9 years
  2. aThe ECHO cohort was created by pooling three individual prospective cohort studies: Conditions Affecting Neurocognitive Development and Learning in Early Childhood (CANDLE), The Infant Development and Environment Study (TIDES), and Global Alliance to Prevent Prematurity and ssssStillbirths (GAPS)