Fig. 1

Dose–response associations of plasma total PFOS, branched PFOS and linear PFOS with the risk of CHD. Note: This analysis was run in the case–control cohort based on conditional logistic regression. The models were adjusted for matching factors (including age, gender, smoking status and date of blood sampling), fasting status (yes or no), BMI (kg/m2), physical activity (MET-hr/wk), alcohol consumption (never, 0–4.9 g/d, 5.0–14.9 g/d, and > 15 g/d), AHEI (continuous), aspirin use (yes or no), regular lipid-lowering medication use (yes or no), family history of MI (yes or no), and history of hypertension (yes or no), diabetes (yes or no) and hypercholesterolemia (yes or no). The x-axis is natural log-transformed total PFOS, brPFOS and nPFOS, respectively; the y-axis represents the hazard ratio of CHD. The lines in the plot show the trend for the association of interest and p-values are showed on the top-left; the shade denotes 95% confidence interval. Abbreviations: PFOS, Perfluorooctane sulfonate; brPFOS, branched PFOS; nPFOS, linear PFOS