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Table 1 Demographic characteristics and serum determinations

From: PM2.5 constituent exposures and maternal circulatory homocysteine in early pregnancy

Parameter

EPL

(n = 162)

NEP

(n = 162)

p-value

Maternal age (years) (mean ± SD)

32.2 ± 4.5

31.9 ± 4.5

0.226

Gestational age (days after ovulation) (mean ± SD)

48.6 ± 10.5

35.1 ± 5.9

< 0.001

Body mass index (mean ± SD)

22.5 ± 3.0

22.2 ± 3.2

0.487

Gravidity (times) [n (%)]

0.537

 ≤ 2

71 (43.8)

62 (38.3)

 3–4

73 (45.1)

87 (53.7)

 ≥ 5

18 (11.1)

13 (8.0)

Parity (times) [n (%)]

< 0.001

 0

55 (34.0)

29 (17.9)

 1

88 (54.3)

92 (56.8)

 ≥ 2

19 (11.7)

41 (25.3)

Maternal education [n (%)]

0.168

 High school or lower

43 (26.5)

48 (29.6)

 College

104 (64.2)

107 (66.0)

 Higher than college

15 (9.3)

7 (4.3)

Family monthly income per capita (Â¥) [n (%)]

0.237

 < 5000

30 (18.5)

39 (24.1)

 5000–7500

59 (36.4)

58 (35.8)

 > 7500

73 (45.1)

65 (40.1)

Interior renovation either at home or work [n (%)]

< 0.001

 ≥ 1 year ago

147 (90.7)

121 (74.7)

 < 1 year ago

15 (9.3)

41 (25.3)

Occupational exposure [n (%)]

0.523

 No

149 (92.0)

153 (94.4)

 Yes

13 (8.0)

9 (5.6)

Alcohol consumption [n (%)]

0.066

 No

141 (87.0)

127 (78.4)

 Yes

21 (13.0)

35 (21.6)

Active smoking [n (%)]

< 0.001

 No

148 (91.4)

119 (73.5)

 Yes

14 (8.6)

43 (26.5)

Passive smoking [n (%)]

0.073

 No

78 (48.1)

94 (58.0)

 Yes

84 (51.9)

68 (42.0)

Serum Hcy (ng/mL) (Median [IQR])

455.7 (253.8)

416.2 (197.6)

0.002

Serum 5-MeTHF (ng/mL) (Median [IQR])

62.3 (18.1)

54.0 (9.8)

< 0.001

LnHcy (mean ± SD)

6.2 ± 0.4

6.1 ± 0.3

< 0.001

Ln5-MeTHF (mean ± SD)

4.2 ± 0.2

4.0 ± 0.1

< 0.001

  1. Note: 5-MeTHF, 5-methyltetrahydrofolate; EPL, early pregnancy loss; Hcy, homocysteine; IQR, interquartile range; Ln5-MeTHF, the natural logarithm of serum 5-MeTHF; LnHcy, the natural logarithm of serum Hcy; NEP, normal early pregnancy; SD, standard deviation