Skip to main content

Table 3 Association between liver function biomarkers and serum- PFAS (adjusted for age and BMI), n=72

From: Per- and poly-fluoroalkyl substances (PFAS) in circulation in a Canadian population: their association with serum-liver enzyme biomarkers and piloting a novel method to reduce serum-PFAS

 

GGT

AST

ALT

PFAS

βa

p-valueb

β

p-value

β

p-value

PFBA

1.377

0.009

0.965

0.649

1.200

0.152

PFHxA

1.129

0.054

1.055

0.171

1.133

0.051

PFHpA

0.978

0.558

1.008

0.735

1.022

0.579

PFOA

1.127

0.281

1.094

0.193

1.117

0.331

PFNA

1.066

0.279

0.993

0.853

0.973

0.654

PFDA

1.099

0.062

0.976

0.445

0.963

0.463

PFUdA

0.994

0.880

0.970

0.217

0.943

0.146

PFHxS

0.968

0.605

1.045

0.259

1.163

0.017

PFOS

1.019

0.841

0.989

0.849

0.999

0.99

GenX

0.979

0.43

0.981

0.245

0.956

0.087

PFOSA

1.203

0.059

1.070

0.266

1.160

0.141

Total PFAS

1.079

0.489

1.034

0.627

1.050

0.66

NASEM PFASsc

1.064

0.614

1.027

0.720

1.100

0.448

  1. aβ = Change in U/L of serum liver biomarker per ng/ml PFAS increase in serum
  2. bMultivariable linear regression
  3. cNASEM PFASs include PFOA, PFNA, PFDA, PFUnDA, PFHxS, PFOS. Me-FOSAA concentrations were below the LOD
Back to article page

Environmental Health

ISSN: 1476-069X