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Table 2 Associations of polycyclic aromatic hydrocarbons, heavy metals, and per- and polyfluoroalkyl substances with lipid indicators among community-dwelling adults

From: Exposure to polycyclic aromatic hydrocarbons, heavy metals, and per- and polyfluoroalkyl substances and their associations with serum lipid profiles in the general Korean adult population

Pollutants

TC

LDL-C

Non-HDL-C

HDL-C

TG

β (95% CI)

β (95% CI)

β (95% CI)

β (95% CI)

β (95% CI)

1-OHP

2.50 (1.09, 3.91)

2.39 (1.14, 3.63)

2.13 (0.77, 3.49)

0.37 (-0.09, 0.83)

-1.29 (-3.36, 0.78)

2-NAP

1.03 (-1.08, 3.14)

0.94 (-0.93, 2.81)

0.87 (-0.95, 2.68)

0.17 (-0.44, 0.78)

-0.36 (-3.52, 2.80)

1-OHPhe

0.53 (-0.62, 1.68)

0.60 (-0.83, 2.03)

0.13 (-1.04, 1.31)

0.40 (-0.11, 0.90)

-2.33 (-5.37, 0.70)

2-OHFlu

0.004 (-1.79, 1.80)

-0.30 (-2.00, 1.40)

-0.16 (-1.89, 1.57)

0.16 (-0.35, 0.68)

0.69 (-2.48, 3.87)

Lead

7.22 (4.31, 10.12)

4.20 (2.08, 6.33)

5.51 (2.60, 8.42)

1.70 (0.56, 2.85)

6.54 (-0.46, 13.53)

Mercury

4.40 (1.72, 7.00)

3.46 (1.17, 5.74)

3.61 (1.30, 5.92)

0.75 (-0.21, 1.72)

0.76 (-5.11, 6.63)

Cadmium

-0.62 (-3.06, 1.82)

0.26 (-1.48, 2.00)

-0.51 (-2.55, 1.54)

-0.11 (-1.13, 0.91)

-3.83 (-10.06, 2.41)

PFOA

3.82 (-1.83, 9.47)

3.70 (1.01, 6.38)

2.95 (-1.48, 7.39)

0.87 (-0.70, 2.43)

-3.72 (-16.73, 9.28)

PFOS

2.00 (-3.26, 7.26)

1.82 (-1.65, 5.29)

2.43 (-1.81, 6.69)

-0.44 (-1.92, 1.05)

3.10 (-3.28, 9.47)

PFHxS

1.13 (-1.50, 3.76)

1.29 (-0.74, 3.32)

0.60 (-1.69, 2.83)

0.56 (-0.23, 1.35)

-3.61 (-11.63, 4.41)

PFNA

4.64 (0.50, 8.79)

4.56 (2.24, 6.88)

3.96 (0.75, 7.17)

0.68 (-0.78, 2.15)

-3.00 (-13.38, 7.38)

PFDeA

4.81 (-0.74, 10.35)

4.92 (1.72, 8.14)

3.63 (-0.53, 7.79)

1.18 (-0.93, 3.28)

-6.49 (-15.83, 2.84)

  1. Abbreviations: TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; Non-HDL-C, non-high-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TG, triglyceride; CI, confidence interval; 1-OHP, 1-hydroxypyrene; 2-NAP, 2-naphthol; 1-OHPhe, 1-hydroxyphenanthrene; 2-OHFlu, 2-hydroxyfluorene; PFOA, perfluorooctanoic acid; PFOS, perfluorooctane sulfonic acid; PFHxS, perfluorohexane sulfonic acid; PFNA, perfluorononanoic acid; PFDeA, perfluorodecanoic acid. Regression coefficients (β) and 95% confidence intervals were estimated using linear regression models incorporating appropriate strata, cluster, and weight variables. The models were adjusted for age, sex, educational level, married or cohabiting, tobacco smoking, alcohol consumption, regular exercise, and body mass index