Table 2 Associations between MDI and prenatal exposures to NO2/PM2.5 by linear regression
Outcome | Exposure | Estimate (95% CI) | Unadjusted P | FDR adj. P |
|---|---|---|---|---|
MDI at age 1 (N = 482) | NO2 at first trimester | -0.278 (-0.407, -0.149) | <0.001 | 0.001 |
NO2 at second trimester | -0.215 (-0.361, -0.069) | 0.004 | 0.024 | |
NO2 at third trimester | -0.142 (-0.298, 0.013) | 0.072 | 0.123 | |
NO2 at entire pregnancy | -0.258 (-0.413, -0.103) | 0.001 | 0.013 | |
PM2.5 at first trimester | -0.270 (-0.531, -0.009) | 0.043 | 0.123 | |
PM2.5 at second trimester | -0.358 (-0.608, -0.108) | 0.005 | 0.025 | |
PM2.5 at third trimester | -0.134 (-0.452, 0.185) | 0.411 | 0.469 | |
PM2.5 at entire pregnancy | -0.663 (-1.078, -0.248) | 0.002 | 0.014 | |
MDI at age 2 (N = 466) | NO2 at first trimester | -0.103 (-0.266, 0.061) | 0.219 | 0.277 |
NO2 at second trimester | -0.176 (-0.358, 0.007) | 0.06 | 0.123 | |
NO2 at third trimester | -0.196 (-0.389, -0.002) | 0.047 | 0.123 | |
NO2 at entire pregnancy | -0.182 (-0.376, 0.013) | 0.068 | 0.123 | |
PM2.5 at first trimester | -0.251 (-0.584, 0.082) | 0.14 | 0.209 | |
PM2.5 at second trimester | -0.062 (-0.381, 0.257) | 0.704 | 0.735 | |
PM2.5 at third trimester | 0.282 (-0.121, 0.684) | 0.17 | 0.226 | |
PM2.5 at entire pregnancy | -0.075 (-0.606, 0.456) | 0.782 | 0.782 | |
MDI at age 3 additionally adjusting for HOME at age 3 (N = 432) | NO2 at first trimester | -0.189 (-0.339, -0.040) | 0.013 | 0.053 |
NO2 at second trimester | -0.125 (-0.289, 0.040) | 0.136 | 0.209 | |
NO2 at third trimester | -0.095 (-0.268, 0.079) | 0.284 | 0.341 | |
NO2 at entire pregnancy | -0.168 (-0.343, 0.008) | 0.062 | 0.123 | |
PM2.5 at first trimester | -0.300 (-0.601, 0.001) | 0.051 | 0.123 | |
PM2.5 at second trimester | -0.208 (-0.494, 0.078) | 0.153 | 0.216 | |
PM2.5 at third trimester | 0.093 (-0.280, 0.465) | 0.626 | 0.683 | |
PM2.5 at entire pregnancy | -0.444 (-0.923, 0.036) | 0.069 | 0.123 |