Table 3 Associations between PDI and prenatal exposures to NO2/PM2.5 by linear regression
Outcome | Exposure | Estimate (95% CI) | Unadjusted P | FDR adj. P |
|---|---|---|---|---|
PDI at age 1 (N = 481) | NO2 at first trimester | -0.042 (-0.201, 0.117) | 0.602 | 0.850 |
NO2 at second trimester | -0.036 (-0.214, 0.143) | 0.695 | 0.852 | |
NO2 at third trimester | -0.023 (-0.212, 0.166) | 0.811 | 0.885 | |
NO2 at entire pregnancy | -0.039 (-0.229, 0.151) | 0.687 | 0.852 | |
PM2.5 at first trimester | -0.099 (-0.417, 0.219) | 0.539 | 0.809 | |
PM2.5 at second trimester | 0.204 (-0.102, 0.509) | 0.19 | 0.508 | |
PM2.5 at third trimester | 0.024 (-0.365, 0.412) | 0.905 | 0.905 | |
PM2.5 at entire pregnancy | 0.096 (-0.412, 0.605) | 0.71 | 0.852 | |
PDI at age 2 (N = 469) | NO2 at first trimester | 0.150 (-0.010, 0.310) | 0.066 | 0.508 |
NO2 at second trimester | 0.137 (-0.042, 0.316) | 0.133 | 0.508 | |
NO2 at third trimester | 0.030 (-0.159, 0.220) | 0.754 | 0.862 | |
NO2 at entire pregnancy | 0.134 (-0.057, 0.324) | 0.169 | 0.508 | |
PM2.5 at first trimester | 0.189 (-0.135, 0.513) | 0.253 | 0.600 | |
PM2.5 at second trimester | 0.134 (-0.177, 0.445) | 0.399 | 0.722 | |
PM2.5 at third trimester | 0.391 (0.001, 0.781) | 0.049 | 0.508 | |
PDI at age 3 additionally adjusting for HOME at age 3 (N = 429) | NO2 at first trimester | 0.074 (-0.107, 0.255) | 0.421 | 0.722 |
NO2 at second trimester | 0.145 (-0.052, 0.343) | 0.149 | 0.508 | |
NO2 at third trimester | 0.079 (-0.130, 0.288) | 0.456 | 0.730 | |
NO2 at entire pregnancy | 0.118 (-0.094, 0.330) | 0.275 | 0.600 | |
PM2.5 at first trimester | 0.036 (-0.331, 0.403) | 0.848 | 0.885 | |
PM2.5 at second trimester | 0.172 (-0.173, 0.517) | 0.328 | 0.656 | |
PM2.5 at third trimester | 0.346 (-0.102, 0.794) | 0.129 | 0.508 | |
PM2.5 at entire pregnancy | 0.405 (-0.174, 0.984) | 0.17 | 0.508 | |
PM2.5 at entire pregnancy | 0.626 (0.113, 1.139) | 0.017 | 0.405 |